TRH and TRH-like peptide levels covary with caloric restriction and oral metformin in rat heart and testis

Background: Obesity, type 2 diabetes, and major depression are common comorbidities in aging populations. Metformin (MF) mimics effects of caloric restriction (CR) which increases health and life spans. CR suppresses central TRH activity resulting in bradycardia and suppression of energy expenditure...

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Detalles Bibliográficos

Autores principales:	Albert Eugene Pekary, Albert Sattin
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2022-06-01
Colección:	Endocrine and Metabolic Science
Materias:	Thyrotropin releasing hormone Metformin Caloric restriction Cardioprotection Testicular function
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2666396122000048
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