TRH and TRH-like peptide levels covary with caloric restriction and oral metformin in rat heart and testis

Background: Obesity, type 2 diabetes, and major depression are common comorbidities in aging populations. Metformin (MF) mimics effects of caloric restriction (CR) which increases health and life spans. CR suppresses central TRH activity resulting in bradycardia and suppression of energy expenditure...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Albert Eugene Pekary, Albert Sattin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2022-06-01
Schriftenreihe:	Endocrine and Metabolic Science
Schlagworte:	Thyrotropin releasing hormone Metformin Caloric restriction Cardioprotection Testicular function
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2666396122000048
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!