Direct detection and identification of active pharmaceutical ingredients in intact tablets by helium plasma ionization (HePI) mass spectrometry

A simple modification converts an electrospray ion source to an ambient-pressure helium plasma ionization source without the need of additional expensive hardware. Peaks for active ingredients were observed in the spectra recorded from intact pharmaceutical tablets placed in this source. A flow of h...

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Hlavní autoři:	Athula B. Attygalle, Freneil B. Jariwala, Julius Pavlov, Zhihua Yang, Jason A. Mahr, Mabel Oviedo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2014-06-01
Edice:	Journal of Pharmaceutical Analysis
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S209517791300107X
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