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The gene expression and bioinformatic analysis of choline trimethylamine-lyase (CutC) and its activating enzyme (CutD) for gut microbes and comparison with their TMA production levels

Recent studies revealed that some intestinal microorganisms anaerobically convert choline to trimethylamine (TMA) by choline TMA-lyase (cutC). TMA is further oxidized to trimethylamine-N-oxide (TMAO), by the liver enzyme flavin-dependent monooxygenase 3 (FMO3). TMA in the serum is correlated with th...

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Principais autores: Latha Ramireddy, Hau-Yang Tsen, Yu-Chen Chiang, Chen Ying Hung, Fu-Chih Chen, Hsien- Tung Yen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021-12-01
coleção:Current Research in Microbial Sciences
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2666517421000249
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