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Structure-guided protein engineering increases enzymatic activities of the SGNH family esterases

Abstract Background Esterases and lipases hydrolyze short-chain esters and long-chain triglycerides, respectively, and therefore play essential roles in the synthesis and decomposition of ester bonds in the pharmaceutical and food industries. Many SGNH family esterases share high similarity in seque...

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Principais autores: Zhengyang Li, Long Li, Yingyi Huo, Zijun Chen, Yu Zhao, Jing Huang, Shuling Jian, Zhen Rong, Di Wu, Jianhua Gan, Xiaojian Hu, Jixi Li, Xue-Wei Xu
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2020-06-01
Series:Biotechnology for Biofuels
Assuntos:
Esterase
SGNH superfamily
Swapped structure
Alkaline adaptability
Acceso en liña:http://link.springer.com/article/10.1186/s13068-020-01742-8
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