Structure-guided protein engineering increases enzymatic activities of the SGNH family esterases

Abstract Background Esterases and lipases hydrolyze short-chain esters and long-chain triglycerides, respectively, and therefore play essential roles in the synthesis and decomposition of ester bonds in the pharmaceutical and food industries. Many SGNH family esterases share high similarity in seque...

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Hlavní autoři:	Zhengyang Li, Long Li, Yingyi Huo, Zijun Chen, Yu Zhao, Jing Huang, Shuling Jian, Zhen Rong, Di Wu, Jianhua Gan, Xiaojian Hu, Jixi Li, Xue-Wei Xu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2020-06-01
Edice:	Biotechnology for Biofuels
Témata:	Esterase SGNH superfamily Swapped structure Alkaline adaptability
On-line přístup:	http://link.springer.com/article/10.1186/s13068-020-01742-8
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