Cancer cell adaptation to hypoxia involves a HIF‐GPRC5A‐YAP axis
Abstract Hypoxia is a hallmark of solid tumours and a key physiological feature distinguishing cancer from normal tissue. However, a major challenge remains in identifying tractable molecular targets that hypoxic cancer cells depend on for survival. Here, we used SILAC‐based proteomics to identify t...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Nature
2018-08-01
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| Serie: | EMBO Molecular Medicine |
| Soggetti: | |
| Accesso online: | https://doi.org/10.15252/emmm.201708699 |
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