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Upregulated GPRC5A disrupting the Hippo pathway promotes the proliferation and migration of pancreatic cancer cells via the cAMP-CREB axis

Abstract Background Pancreatic cancer has a high mortality rate worldwide, and is predicted to be third leading cause of death in the near future. However, the regulatory mechanisms that inhibit the progression of pancreatic cancer remain elusive. Currently, exploring the function and mechanisms of...

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Hlavní autoři: Weidan Fang, Xin Yu, Jun Deng, Bin Yu, Jianping Xiong, Mei Ma
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer 2023-02-01
Edice:Discover Oncology
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On-line přístup:https://doi.org/10.1007/s12672-023-00626-1
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