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Upregulated GPRC5A disrupting the Hippo pathway promotes the proliferation and migration of pancreatic cancer cells via the cAMP-CREB axis

Abstract Background Pancreatic cancer has a high mortality rate worldwide, and is predicted to be third leading cause of death in the near future. However, the regulatory mechanisms that inhibit the progression of pancreatic cancer remain elusive. Currently, exploring the function and mechanisms of...

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Autors principals: Weidan Fang, Xin Yu, Jun Deng, Bin Yu, Jianping Xiong, Mei Ma
Format: Artigo
Idioma:Inglês
Publicat: Springer 2023-02-01
Col·lecció:Discover Oncology
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Accés en línia:https://doi.org/10.1007/s12672-023-00626-1
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