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Cancer cell adaptation to hypoxia involves a HIF‐GPRC5A‐YAP axis

Abstract Hypoxia is a hallmark of solid tumours and a key physiological feature distinguishing cancer from normal tissue. However, a major challenge remains in identifying tractable molecular targets that hypoxic cancer cells depend on for survival. Here, we used SILAC‐based proteomics to identify t...

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Xehetasun bibliografikoak
Egile Nagusiak: Alexander Greenhough, Clare Bagley, Kate J Heesom, David B Gurevich, David Gay, Mark Bond, Tracey J Collard, Chris Paraskeva, Paul Martin, Owen J Sansom, Karim Malik, Ann C Williams
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Nature 2018-08-01
Saila:EMBO Molecular Medicine
Gaiak:
Sarrera elektronikoa:https://doi.org/10.15252/emmm.201708699
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