High-dose treatment of cathepsin B-activatable doxorubicin prodrug nanoparticles that induce tumor-specific immunogenic cell death for immunotherapy of melanoma with minimal systemic toxicity

Highly potent chemotherapy provides rapid therapeutic efficacy in melanoma, but is often limited by drug resistance, off-target toxicity, and systemic toxicity. Combination therapy with chemotherapy and immunotherapy has attracted much attention but still faces challenges such as inconsistent immune...

Szczegółowa specyfikacja

Opis bibliograficzny

Główni autorzy:	Yoojeong Oh, Jinseong Kim, Nayeon Shim, Hyeonji Yoo, Hoyeon Lee, Yumin Jeong, Jagyeong Goo, Jeongyeon Lee, Mihee Jo, Hanhee Cho, Kwangmeyung Kim
Format:	Artigo
Język:	Inglês
Wydane:	KeAi Communications Co., Ltd. 2026-02-01
Seria:	Asian Journal of Pharmaceutical Sciences
Hasła przedmiotowe:	Cathepsin B-activatable prodrug Doxorubicin Melanoma Immunogenic cell death Immune checkpoint blockade Chemo-immunotherapy
Dostęp online:	http://www.sciencedirect.com/science/article/pii/S1818087626000097
Etykiety:	Dodaj etykietę Nie ma etykietki, Dołącz pierwszą etykiete!