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Unique mode of binding between angiotensin II type 1 receptor and its blockers

BACKGROUND: We hypothesized that the 5-oxo-1,2,4-oxadiazole moiety of azilsartan (AZL), which represents a small difference in the molecular structures of AZL and candesartan (CAN) [angiotensin II type 1 receptor (AT1R) blockers], may be responsible for the molecular effects of AZL. METHODS: We exam...

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Detaylı Bibliyografya
Asıl Yazarlar: Yoshino Matsuo, Yasunori Suematsu, Sayo Tomita, Kohei Tashiro, Takashi Kuwano, Ken Kitajima, Shin-ichiro Miura
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis Group 2019-11-01
Seri Bilgileri:Clinical and Experimental Hypertension
Konular:
Online Erişim:http://dx.doi.org/10.1080/10641963.2018.1545851
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