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Ligand-independent signals from angiotensin II type 2 receptor induce apoptosis
Conventional models of ligand–receptor regulation predict that agonists enhance the tone of signals generated by the receptor in the absence of ligand. Contrary to this paradigm, stimulation of the type 2 (AT(2)) receptor by angiotensin II (Ang II) is not required for induction of apoptosis but the...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306598/ https://ncbi.nlm.nih.gov/pubmed/10921883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.15.4026 |
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