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Ligand-independent signals from angiotensin II type 2 receptor induce apoptosis

Conventional models of ligand–receptor regulation predict that agonists enhance the tone of signals generated by the receptor in the absence of ligand. Contrary to this paradigm, stimulation of the type 2 (AT(2)) receptor by angiotensin II (Ang II) is not required for induction of apoptosis but the...

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Detalhes bibliográficos
Main Authors: Miura, Shin-ichiro, Karnik, Sadashiva S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC306598/
https://ncbi.nlm.nih.gov/pubmed/10921883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.15.4026
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