Unique mode of binding between angiotensin II type 1 receptor and its blockers
BACKGROUND: We hypothesized that the 5-oxo-1,2,4-oxadiazole moiety of azilsartan (AZL), which represents a small difference in the molecular structures of AZL and candesartan (CAN) [angiotensin II type 1 receptor (AT1R) blockers], may be responsible for the molecular effects of AZL. METHODS: We exam...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis Group
2019-11-01
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| Schriftenreihe: | Clinical and Experimental Hypertension |
| Schlagworte: | |
| Online-Zugang: | http://dx.doi.org/10.1080/10641963.2018.1545851 |
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