Decursin induces FLT3-ITD acute myeloid leukemia cell apoptosis by increasing the expression of the ubiquitin-conjugase UBE2L6
Abstract Mutation in the internal tandem duplication sequence of the FLT3 gene (FLT3-ITD) is linked to a poor clinical prognosis in acute myeloid leukemia (AML) patients. FLT3 inhibitors have demonstrated efficacy in improving the prognosis of AML patients with FLT3-ITD. However, the efficacy of FLT...
Gardado en:
| Principais autores: | , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BMC
2025-04-01
|
| Series: | Cell Communication and Signaling |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1186/s12964-025-02157-4 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|