Integrating FLT3-ITD molecular features with clinical risk factors improves risk stratification in acute myeloid leukemia

Abstract This study aimed to investigate the prognostic value of FLT3-ITD molecular features such as allelic ratio (AR), variant allele frequency (VAF), insertion length, insertion number and insertion site in patients with de novo acute myeloid leukemia (AML). Next-generation sequencing (NGS) was u...

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Principais autores:	Kainan Zhang, Xiaohang Ma, Xiaoxuan Lu, Guorui Ruan, Fangfang Wei, Hao Jiang, Yingjun Chang, Xiaojun Huang, Xiaosu Zhao
格式:	Artigo
語言:	Inglês
出版:	Springer 2026-01-01
叢編:	Annals of Hematology
主題:	Acute myeloid leukemia Prognosis FLT3-ITD Molecular
在線閱讀:	https://doi.org/10.1007/s00277-026-06802-x
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