Lactate metabolism-driven lactylation: paradoxical modulation of intestinal inflammation and malignancy

Abstract Background Intestinal inflammation and malignancy represent two critical pathological states in the gut that severely impair patients’ quality of life. Understanding their molecular mechanisms holds significant therapeutic implications. Lactate plays a key role in cellular signaling and imm...

Полное описание

Библиографические подробности

Главные авторы:	Junting Liu, Yilong Liu, Hao Zhang, Zhaoshen Li, Xue Fang, Zixuan He, Yu Bai
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2026-04-01
Серии:	Journal of Translational Medicine
Предметы:	Lactylation Lactate Inflammatory bowel disease Colorectal cancer Paradoxical modulation
Online-ссылка:	https://doi.org/10.1186/s12967-026-08041-0
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!