The inactivation of RNase G reduces the Stenotrophomonas maltophilia susceptibility to quinolones by triggering the heat shock response.

Quinolone resistance is usually due to mutations in the genes encoding bacterial topoisomerases. However different reports have shown that neither clinical quinolone resistant isolates nor in vitro obtained S. maltophilia mutants present mutations in such genes. The mechanisms so far described cons...

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Bibliografski detalji

Glavni autori:	Alejandra eBernardini, Fernando eCorona, Ricardo eDias, Maria Blanca Sanchez, Jose L Martinez
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2015-10-01
Serija:	Frontiers in Microbiology
Teme:	Stenotrophomonas maltophilia antibiotic resistance Quinolone resistance RNase G Heat shock.
Online pristup:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01068/full
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