The inactivation of RNase G reduces the Stenotrophomonas maltophilia susceptibility to quinolones by triggering the heat shock response.

Quinolone resistance is usually due to mutations in the genes encoding bacterial topoisomerases. However different reports have shown that neither clinical quinolone resistant isolates nor in vitro obtained S. maltophilia mutants present mutations in such genes. The mechanisms so far described cons...

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Библиографические подробности

Главные авторы:	Alejandra eBernardini, Fernando eCorona, Ricardo eDias, Maria Blanca Sanchez, Jose L Martinez
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2015-10-01
Серии:	Frontiers in Microbiology
Предметы:	Stenotrophomonas maltophilia antibiotic resistance Quinolone resistance RNase G Heat shock.
Online-ссылка:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01068/full
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