The inactivation of RNase G reduces the Stenotrophomonas maltophilia susceptibility to quinolones by triggering the heat shock response.

Quinolone resistance is usually due to mutations in the genes encoding bacterial topoisomerases. However different reports have shown that neither clinical quinolone resistant isolates nor in vitro obtained S. maltophilia mutants present mutations in such genes. The mechanisms so far described cons...

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Hlavní autoři:	Alejandra eBernardini, Fernando eCorona, Ricardo eDias, Maria Blanca Sanchez, Jose L Martinez
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2015-10-01
Edice:	Frontiers in Microbiology
Témata:	Stenotrophomonas maltophilia antibiotic resistance Quinolone resistance RNase G Heat shock.
On-line přístup:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01068/full
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