Loss of miR-145 promotes remyelination and functional recovery in a model of chronic central demyelination
Abstract Strategies for treating progressive multiple sclerosis (MS) remain limited. Here, we found that miR-145-5p is overabundant uniquely in chronic lesion tissues from secondary progressive MS patients. We induced both acute and chronic demyelination in miR-145 knockout mice to determine its con...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Portfolio
2024-07-01
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| Seri Bilgileri: | Communications Biology |
| Online Erişim: | https://doi.org/10.1038/s42003-024-06513-x |
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