Loss of miR-145 promotes remyelination and functional recovery in a model of chronic central demyelination
Abstract Strategies for treating progressive multiple sclerosis (MS) remain limited. Here, we found that miR-145-5p is overabundant uniquely in chronic lesion tissues from secondary progressive MS patients. We induced both acute and chronic demyelination in miR-145 knockout mice to determine its con...
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| Автори: | , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Nature Portfolio
2024-07-01
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| Серія: | Communications Biology |
| Онлайн доступ: | https://doi.org/10.1038/s42003-024-06513-x |
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