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Rates of lobar atrophy in asymptomatic MAPT mutation carriers

Abstract Introduction The aim of this study was to investigate the rates of lobar atrophy in the asymptomatic microtubule‐associated protein tau (MAPT) mutation carriers. Methods MAPT mutation carriers (n = 14; 10 asymptomatic, 4 converters from asymptomatic to symptomatic) and noncarriers (n = 13)...

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Autores principales: Qin Chen, Bradley F. Boeve, Matthew Senjem, Nirubol Tosakulwong, Timothy G. Lesnick, Danielle Brushaber, Christina Dheel, Julie Fields, Leah Forsberg, Ralitza Gavrilova, Debra Gearhart, Jonathan Graff‐Radford, Neill R. Graff‐Radford, Clifford R. Jack Jr., David T. Jones, David S. Knopman, Walter K. Kremers, Maria Lapid, Rosa Rademakers, Jeremy Syrjanen, Adam L. Boxer, Howie Rosen, Zbigniew K. Wszolek, Kejal Kantarci, LEFFTDS Consortium
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley 2019-01-01
Colección:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Materias:
Frontotemporal dementia
Magnetic resonance image
MAPT
Asymptomatic
Longitudinal
Acceso en línea:https://doi.org/10.1016/j.trci.2019.05.010
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