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Rates of lobar atrophy in asymptomatic MAPT mutation carriers

Abstract Introduction The aim of this study was to investigate the rates of lobar atrophy in the asymptomatic microtubule‐associated protein tau (MAPT) mutation carriers. Methods MAPT mutation carriers (n = 14; 10 asymptomatic, 4 converters from asymptomatic to symptomatic) and noncarriers (n = 13)...

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Auteurs principaux: Qin Chen, Bradley F. Boeve, Matthew Senjem, Nirubol Tosakulwong, Timothy G. Lesnick, Danielle Brushaber, Christina Dheel, Julie Fields, Leah Forsberg, Ralitza Gavrilova, Debra Gearhart, Jonathan Graff‐Radford, Neill R. Graff‐Radford, Clifford R. Jack Jr., David T. Jones, David S. Knopman, Walter K. Kremers, Maria Lapid, Rosa Rademakers, Jeremy Syrjanen, Adam L. Boxer, Howie Rosen, Zbigniew K. Wszolek, Kejal Kantarci, LEFFTDS Consortium
Format: Artigo
Langue:Inglês
Publié: Wiley 2019-01-01
Collection:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Sujets:
Frontotemporal dementia
Magnetic resonance image
MAPT
Asymptomatic
Longitudinal
Accès en ligne:https://doi.org/10.1016/j.trci.2019.05.010
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