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Profiling DNA damage response following mitotic perturbations

DNA damage arising from replication stress is well studied, but the effect of mitotic errors on genome integrity is less understood. Here the authors knock down 47 mitotic regulators and record how they impact on DNA breakage events, providing a resource for future studies on the relation between ce...

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Hlavní autoři: Ronni S. Pedersen, Gopal Karemore, Thorkell Gudjonsson, Maj-Britt Rask, Beate Neumann, Jean-Karim Hériché, Rainer Pepperkok, Jan Ellenberg, Daniel W. Gerlich, Jiri Lukas, Claudia Lukas
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2016-12-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/ncomms13887
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