Mitotic gene regulation by the N-MYC-WDR5-PDPK1 nexus

Abstract Background During mitosis the cell depends on proper attachment and segregation of replicated chromosomes to generate two identical progeny. In cancers defined by overexpression or dysregulation of the MYC oncogene this process becomes impaired, leading to genomic instability and tumor evol...

詳細記述

書誌詳細

主要な著者:	Sarah A. Streeter, Alexandria G. Williams, James R. Evans, Jing Wang, Alissa D. Guarnaccia, Andrea C. Florian, Rafet Al-Tobasei, Qi Liu, William P. Tansey, April M. Weissmiller
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2024-04-01
シリーズ:	BMC Genomics
主題:	N-MYC WDR5 PDPK1 Mitosis Chromosome segregation Spindle pole
オンライン･アクセス:	https://doi.org/10.1186/s12864-024-10282-6
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!