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Structural analysis of the dynamic ribosome-translocon complex

The protein translocon at the endoplasmic reticulum comprises the Sec61 translocation channel and numerous accessory factors that collectively facilitate the biogenesis of secretory and membrane proteins. Here, we leveraged recent advances in cryo-electron microscopy (cryo-EM) and structure predicti...

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Bibliographic Details
Main Authors: Aaron JO Lewis, Frank Zhong, Robert J Keenan, Ramanujan S Hegde
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications Ltd 2024-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/95814
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