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Martini compatible coarse-grained model of polyethylenimine for pulmonary gene delivery

Abstract Pulmonary gene delivery has demonstrated high specificity for respiratory diseases, offering great control on dosage of therapeutics and side effects. On the other hand, intrinsic barriers in pulmonary systems impose new challenges such as crossing the pulmonary surfactant and evading mucus...

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Bibliografische Detailangaben
Hauptverfasser: Graham Lunt, Niloofar Hashemi, Subhamoy Mahajan, Tian Tang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2025-02-01
Schriftenreihe:Scientific Reports
Schlagworte:
Online-Zugang:https://doi.org/10.1038/s41598-025-88848-x
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