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Martini compatible coarse-grained model of polyethylenimine for pulmonary gene delivery

Abstract Pulmonary gene delivery has demonstrated high specificity for respiratory diseases, offering great control on dosage of therapeutics and side effects. On the other hand, intrinsic barriers in pulmonary systems impose new challenges such as crossing the pulmonary surfactant and evading mucus...

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Autori principali: Graham Lunt, Niloofar Hashemi, Subhamoy Mahajan, Tian Tang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-02-01
Serie:Scientific Reports
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Accesso online:https://doi.org/10.1038/s41598-025-88848-x
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