Unraveling Human AQP5-PIP Molecular Interaction and Effect on AQP5 Salivary Glands Localization in SS Patients

Saliva secretion requires effective translocation of aquaporin 5 (AQP5) water channel to the salivary glands (SGs) acinar apical membrane. Patients with Sjögren’s syndrome (SS) display abnormal AQP5 localization within acinar cells from SGs that correlate with sicca manifestation and glands hypofunc...

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Detalhes bibliográficos

Principais autores:	Clara Chivasso, Veronika Nesverova, Michael Järvå, Anne Blanchard, Kristie L Rose, Fredrik Kryh Öberg, Zhen Wang, Maud Martin, Florent Lhotellerie, Egor Zindy, Bruna Junqueira, Karelle Leroy, Benoit Vanhollebeke, Valérie Delforge, Nargis Bolaky, Jason Perret, Muhammad Shahnawaz Soyfoo, Stefania Moscato, Chiara Baldini, François Chaumont, Letizia Mattii, Kevin L Schey, Yvonne Myal, Susanna Törnroth-Horsefield, Christine Delporte
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-08-01
coleção:	Cells
Assuntos:	aquaporin-5 Sjögren’s syndrome prolactin-inducible protein salivary gland
Acesso em linha:	https://www.mdpi.com/2073-4409/10/8/2108
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