A therapeutic-grade purified exosome system alleviates osteoarthritis by regulating autophagy through the BCL2–Beclin1 axis

Abstract Background Osteoarthritis is a common and progressive degenerative joint disorder marked by cartilage degradation, subchondral bone remodeling, and chondrocyte apoptosis. Autophagy, a tightly regulated intracellular degradation process, is essential for maintaining chondrocyte homeostasis....

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Gongyin Zhao, Farbod Yousefi, Ichiro Tsukamoto, Steven Moran, Atta Behfar, Christopher Evans, Chunfeng Zhao
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2025-12-01
Цуврал:	Journal of Nanobiotechnology
Нөхцлүүд:	Exosomes Autophagy Apoptosis BCL2 Beclin-1 Cartilage regeneration
Онлайн хандалт:	https://doi.org/10.1186/s12951-025-03807-y
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!