Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts
Aging is associated with progressive and site-specific changes in DNA methylation (DNAm). These global changes are captured by DNAm clocks that accurately predict chronological age in humans but relatively little is known about how clocks perform in vitro. Here we culture primary human fibroblasts a...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis Group
2019-10-01
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| Col·lecció: | Epigenetics |
| Matèries: | |
| Accés en línia: | http://dx.doi.org/10.1080/15592294.2019.1626651 |
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