Heritable ER stress impairs mitochondrial metabolism and maintenance of hematopoietic stem cells after low-dose irradiation

Summary: How hematopoietic stem cells (HSCs) respond to low doses of radiation currently used in medicine is largely unknown. Here, we show that HSC exposed to a single 20 mGy dose of irradiation (20 mGy-HSC) exhibit, when proliferating, oxidative stress and altered metabolism associated with increa...

Descripción completa

Detalles Bibliográficos

Autores principales:	Stephanie G. Moreno, Federica Ferri, Daniel Lewandowski, Vilma Barroca, Saiyiramii Devanand, Nathalie Dechamps, Paul-Henri Romeo, Nathalie Gault
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2026-02-01
Colección:	iScience
Materias:	Cell biology
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2589004226001136
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!