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Osteoarthritis increases the risk of inflammatory arthritis due to immune checkpoint inhibitors associated with tissue-resident memory T cells

Objective Immune checkpoint inhibitors (ICIs) have significantly advanced cancer treatment, but they can also lead to immune-related adverse events (irAEs), including inflammatory arthritis. Understanding the risk factors and underlying mechanisms of irAE pathogenesis is crucial for optimal patient...

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Hlavní autoři: Yevgeniya Gartshteyn, Brian S Henick, Robert J Winchester, Adam Mor, Matthieu Paiola, Daniel M Portnoy, Luke Yi Hao, Shoiab Bukhari
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2025-03-01
Edice:Journal for ImmunoTherapy of Cancer
On-line přístup:https://jitc.bmj.com/content/13/3/e010758.full
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