Environmental pH and peptide signaling control virulence of Streptococcus pyogenes via a quorum-sensing pathway

The mechanism by which environmental pH controls the virulence of the pathogen Streptococcus pyogenes is unclear. Here, Do et al. show that changes in pH affect the activity of the virulence regulator RopB via its interaction with a quorum-sensing peptide signal.

Detalles Bibliográficos

Autores principales:	Hackwon Do, Nishanth Makthal, Arica R. VanderWal, Matthew Ojeda Saavedra, Randall J. Olsen, James M. Musser, Muthiah Kumaraswami
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2019-06-01
Colección:	Nature Communications
Acceso en línea:	https://doi.org/10.1038/s41467-019-10556-8
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