Environmental pH and peptide signaling control virulence of Streptococcus pyogenes via a quorum-sensing pathway

The mechanism by which environmental pH controls the virulence of the pathogen Streptococcus pyogenes is unclear. Here, Do et al. show that changes in pH affect the activity of the virulence regulator RopB via its interaction with a quorum-sensing peptide signal.

Dades bibliogràfiques

Autors principals:	Hackwon Do, Nishanth Makthal, Arica R. VanderWal, Matthew Ojeda Saavedra, Randall J. Olsen, James M. Musser, Muthiah Kumaraswami
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2019-06-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-019-10556-8
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