Different contributions of YAP1 and TAZ in the regulation of GIST tumorigenic properties

Abstract Background Gastrointestinal stromal tumors (GIST) are mainly caused by gain-of-function mutations in KIT or PDGFRA genes and constitute the most common malignant neoplasm of mesenchymal origin. Dysregulation of the Hippo pathway and its downstream effectors YAP1 and TAZ has been implicated...

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Autors principals:	Irène Pezzati, Thania Hammoum, Clémentine Ayélé Teko-Agbo, Karidia Konate, Mathieu Beranger, Eric Vivès, Frédéric Chibon, Sandrine Faure, Pascal de Santa Barbara, César Serrano, Sébastien Deshayes, Prisca Boisguérin
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-04-01
Col·lecció:	Cell Communication and Signaling
Matèries:	GIST YAP1 TAZ siRNA WRAP5 Nanoparticle
Accés en línia:	https://doi.org/10.1186/s12964-026-02859-3
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