QR-Code

Different contributions of YAP1 and TAZ in the regulation of GIST tumorigenic properties

Abstract Background Gastrointestinal stromal tumors (GIST) are mainly caused by gain-of-function mutations in KIT or PDGFRA genes and constitute the most common malignant neoplasm of mesenchymal origin. Dysregulation of the Hippo pathway and its downstream effectors YAP1 and TAZ has been implicated...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Irène Pezzati, Thania Hammoum, Clémentine Ayélé Teko-Agbo, Karidia Konate, Mathieu Beranger, Eric Vivès, Frédéric Chibon, Sandrine Faure, Pascal de Santa Barbara, César Serrano, Sébastien Deshayes, Prisca Boisguérin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2026-04-01
Schriftenreihe:Cell Communication and Signaling
Schlagworte:
GIST
YAP1
TAZ
siRNA
WRAP5
Nanoparticle
Online-Zugang:https://doi.org/10.1186/s12964-026-02859-3
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!

Ähnliche Einträge