WRAP-based nanoparticles for siRNA delivery: a SAR study and a comparison with lipid-based transfection reagents

Abstract Recently, we designed novel amphipathic cell-penetrating peptides, called WRAP, able to transfer efficiently siRNA molecules into cells. In order to gain more information about the relationship between amino acid composition, nanoparticle formation and cellular internalization of these pept...

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Detalhes bibliográficos

Principais autores:	Karidia Konate, Emilie Josse, Milana Tasic, Karima Redjatti, Gudrun Aldrian, Sébastien Deshayes, Prisca Boisguérin, Eric Vivès
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-08-01
coleção:	Journal of Nanobiotechnology
Assuntos:	Cell-penetrating peptides Nanoparticle siRNA delivery Structure–activity relationship
Acesso em linha:	https://doi.org/10.1186/s12951-021-00972-8
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