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Simulation of pH-Dependent Conformational Transitions in Membrane Proteins: The CLC-ec1 Cl<sup>−</sup>/H<sup>+</sup> Antiporter

Intracellular transport of chloride by members of the CLC transporter family involves a coupled exchange between a Cl<sup>−</sup> anion and a proton (H<sup>+</sup>), which makes the transport function dependent on ambient pH. Transport activity peaks at pH 4.5 and stalls at neutral pH. However, a st...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Ekaterina Kots, Derek M. Shore, Harel Weinstein
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2021-11-01
Rangatū:Molecules
Ngā marau:
Urunga tuihono:https://www.mdpi.com/1420-3049/26/22/6956
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