A Mathematical Model of Lysosomal Ion Homeostasis Points to Differential Effects of Cl⁻ Transport in Ca²⁺ Dynamics

The establishment and maintenance of ion gradients between the interior of lysosomes and the cytosol are crucial for numerous cellular and organismal functions. Numerous ion transport proteins ensure the required variation in luminal concentrations of the different ions along the endocytic pathway t...

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Hlavní autoři:	Rosario Astaburuaga, Orlando Daniel Quintanar Haro, Tobias Stauber, Angela Relógio
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2019-10-01
Edice:	Cells
Témata:	mathematical modelling lysosomal homeostasis slowly voltage-gated chloride transport lysosomal ca<sup>2+</sup> dynamics
On-line přístup:	https://www.mdpi.com/2073-4409/8/10/1263
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