Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory Response

Double-stranded DNA (dsDNA) sensor cyclic-GMP-AMP synthase (cGAS) along with the downstream stimulator of interferon genes (STING) acting as essential immune-surveillance mediators have become hot topics of research. The intrinsic function of the cGAS-STING pathway facilitates type-I interferon (IFN...

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Hlavní autoři:	Dongshan Wan, Wei Jiang, Junwei Hao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2020-04-01
Edice:	Frontiers in Immunology
Témata:	inflammation cGAS STING cGAMP type I interferonopathies
On-line přístup:	https://www.frontiersin.org/article/10.3389/fimmu.2020.00615/full
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