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cGAS-STING, an important pathway in cancer immunotherapy

Abstract Cytosolic DNA sensing, the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway, is an important novel role in the immune system. Multiple STING agonists were developed for cancer therapy study with great results achieved in pre-clinical work. Recent progress in the m...

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Détails bibliographiques
Auteurs principaux: Minlin Jiang, Peixin Chen, Lei Wang, Wei Li, Bin Chen, Yu Liu, Hao Wang, Sha Zhao, Lingyun Ye, Yayi He, Caicun Zhou
Format: Artigo
Langue:Inglês
Publié: BMC 2020-06-01
Collection:Journal of Hematology & Oncology
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Accès en ligne:http://link.springer.com/article/10.1186/s13045-020-00916-z
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