Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator

Abstract Chromatin acetylation, a critical regulator of synaptic plasticity and memory processes, is thought to be altered in neurodegenerative diseases. Here, we demonstrate that spatial memory and plasticity (LTD, dendritic spine formation) deficits can be restored in a mouse model of tauopathy fo...

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Detalles Bibliográficos

Principais autores:	Snehajyoti Chatterjee, Raphaelle Cassel, Anne Schneider‐Anthony, Karine Merienne, Brigitte Cosquer, Laura Tzeplaeff, Sarmistha Halder Sinha, Manoj Kumar, Piyush Chaturbedy, Muthusamy Eswaramoorthy, Stéphanie Le Gras, Céline Keime, Olivier Bousiges, Patrick Dutar, Petnoi Petsophonsakul, Claire Rampon, Jean‐Christophe Cassel, Luc Buée, David Blum, Tapas K Kundu, Anne‐Laurence Boutillier
Formato:	Artigo
Idioma:	Inglês
Publicado:	Springer Nature 2018-10-01
Series:	EMBO Molecular Medicine
Assuntos:	acetylation Alzheimer's disease CREB‐binding protein learning transcription
Acceso en liña:	https://doi.org/10.15252/emmm.201708587
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