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Integrative In Silico and In Vitro Evaluation of Tucatinib as a Potent Inhibitor of TTK Kinase and Cancer Cell Migration

Human TTK (Mps1) kinase is a pivotal regulator of the spindle assembly checkpoint and a high-priority target for antineoplastic interventions. This study employed an integrative pipeline—combining in silico molecular modeling with in vitro biological validation—to evaluate the inhibitory potential o...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Zahraa Hashim, Dhurgham Al-Fahad
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Assiut University, Faculty of Pharmacy 2026-06-01
Цуврал:Bulletin of Pharmaceutical Sciences. Assiut University
Нөхцлүүд:
Онлайн хандалт:https://bpsa.journals.ekb.eg/article_510397.html
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