Medium-Chain Acyl-CoA Dehydrogenase Deficiency in Gene-Targeted Mice.
Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is the most common inherited disorder of mitochondrial fatty acid beta-oxidation in humans. To better understand the pathogenesis of this disease, we developed a mouse model for MCAD deficiency (MCAD) by gene targeting in embryonic stem (ES) cell...
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| Formato: | Artigo |
|---|---|
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2005-08-01
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| coleção: | PLoS Genetics |
| Acesso em linha: | http://dx.doi.org/10.1371/journal.pgen.0010023 |
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