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Medium-Chain Acyl-CoA Dehydrogenase Deficiency in Gene-Targeted Mice.

Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is the most common inherited disorder of mitochondrial fatty acid beta-oxidation in humans. To better understand the pathogenesis of this disease, we developed a mouse model for MCAD deficiency (MCAD) by gene targeting in embryonic stem (ES) cell...

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Xehetasun bibliografikoak
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science (PLoS) 2005-08-01
Saila:PLoS Genetics
Sarrera elektronikoa:http://dx.doi.org/10.1371/journal.pgen.0010023
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