CCR5 conformations are dynamic and modulated by localization, trafficking and G protein association.
CCR5 acts as the principal coreceptor during HIV-1 transmission and early stages of infection. Efficient HIV-1 entry requires a series of processes, many dependent on the conformational state of both viral envelope protein and cellular receptor. Monoclonal antibodies (MAbs) are able to identify diff...
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| Principais autores: | , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Public Library of Science (PLoS)
2014-01-01
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| 丛编: | PLoS ONE |
| 在线阅读: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089056&type=printable |
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