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CCR5 conformations are dynamic and modulated by localization, trafficking and G protein association.

CCR5 acts as the principal coreceptor during HIV-1 transmission and early stages of infection. Efficient HIV-1 entry requires a series of processes, many dependent on the conformational state of both viral envelope protein and cellular receptor. Monoclonal antibodies (MAbs) are able to identify diff...

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Váldodahkkit: Ayanna J Flegler, Gianguido C Cianci, Thomas J Hope
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2014-01-01
Ráidu:PLoS ONE
Liŋkkat:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089056&type=printable
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