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Epigenetic crosstalk between hypoxia and tumor driven by HIF regulation

Abstract Hypoxia is the major influence factor in physiological and pathological courses which are mainly mediated by hypoxia-inducible factors (HIFs) in response to low oxygen tensions within solid tumors. Under normoxia, HIF signaling pathway is inhibited due to HIF-α subunits degradation. However...

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Bibliografische Detailangaben
Hauptverfasser: Tiansheng Li, Chao Mao, Xiang Wang, Ying Shi, Yongguang Tao
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2020-10-01
Schriftenreihe:Journal of Experimental & Clinical Cancer Research
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Online-Zugang:http://link.springer.com/article/10.1186/s13046-020-01733-5
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